Who first observed ribosomes in the mid-1950s and described them as small particles in the cytoplasm that were preferentially attached to the endoplasmic reticulum membrane?
Show answer & explanation
Correct answer: D
Explanation
The correct answer is option 4 i.e. George Palade.
The first to observe ribosomes and describe them as small particles attached to the endoplasmic reticulum membrane in the mid-1950s was George Palade. His pioneering work using electron microscopy allowed him to visualize these structures in detail and understand their role in protein synthesis. Palade's contributions were crucial in elucidating the function of ribosomes and the structure of the endoplasmic reticulum, significantly advancing cell biology. For this work, he was awarded the Nobel Prize in Physiology or Medicine in 1974.