Which Indian organization developed the world’s first DNA vaccine for COVID-19, known as ZyCoV-D?
Show answer & explanation
Correct answer: C
Explanation
Correct Answer
Zydus Cadila
Explanation
ZyCoV-D, the world’s first needle-free plasmid DNA vaccine for COVID-19, was developed by the Indian pharmaceutical company Zydus Cadila (now Zydus Lifesciences). Unlike traditional vaccines that use inactivated viruses or viral vectors, ZyCoV-D uses a plasmid DNA platform. When administered, this DNA instructs the body's cells to produce the spike protein of the SARS-CoV-2 virus, thereby triggering an immune response. This innovative approach offers high stability and can be administered using a needle-free applicator, which reduces the risk of injuries and contamination associated with needles.
Key Points
The development of ZyCoV-D was a significant technological milestone for India’s pharmaceutical sector. It was approved by the Drug Controller General of India (DCGI) for emergency use in individuals aged 12 years and above. The vaccine demonstrated the potential of DNA technology in managing viral outbreaks, proving particularly useful due to its ease of storage and administration.
Important Questions and Answers
Question: What makes the administration of ZyCoV-D unique compared to other COVID-19 vaccines?
Answer: It is administered using a needle-free, painless applicator (the PharmaJet Tropis system) rather than a traditional syringe.
Question: What is the target of the ZyCoV-D vaccine?
Answer: It targets the spike protein of the SARS-CoV-2 virus to generate a protective immune response.