What is the main objective of the ‘Genome India Project’?
Show answer & explanation
Correct answer: B
Explanation
Correct Answer
Map genetic diversity of Indians
Explanation
The primary objective of the Genome India Project is to sequence and map the whole genome of thousands of Indian citizens to build a comprehensive reference database of the genetic diversity unique to the Indian subcontinent. India has an incredibly diverse population composed of over 4600 distinct population groups, many of which have practiced endogamy for generations. This practice has led to unique genetic variations and a distinct burden of genetic diseases. By mapping this vast diversity, researchers can identify specific genetic mutations linked to various diseases, which will pave the way for precision medicine, customized diagnostic tools, and targeted healthcare strategies tailored to the Indian population.
Key Points
The project successfully achieved its initial milestone of sequencing 10000 whole genomes from diverse population groups across the country, creating an invaluable grid for future bio-medical research.
It is a multi-institutional initiative led by the Centre for Brain Research at the Indian Institute of Science (IISc) Bengaluru, involving collaboration with over 20 premier research institutions across India.
The data generated is stored at the Indian Biological Data Centre (IBDC) in Faridabad, ensuring data security and accessibility for indigenous scientific research.
Important Questions and Answers
Question: Which nodal department of the Government of India funds and supports the Genome India Project?
Answer: The Department of Biotechnology (DBT) under the Ministry of Science and Technology funds the initiative.
Question: What is the primary medical benefit of establishing an Indian-specific reference genome database?
Answer: It enables precision medicine and personalized healthcare by identifying population-specific genetic risk factors for rare and complex diseases.