SSC CGL 2025 PYQ — Question 36

SSC CGL - 13 Sep 2025 - Shift 1 • General Awareness • Q36

Telomerase enzyme mainly carries out which of the following functions in a cell?

Show answer & explanation

Correct answer: A

Explanation

The correct answer is option 1 i.e. Extending the length of telomeres.

The correct function of the telomerase enzyme is Extending the length of telomeres.

Telomerase is a specialized ribonucleoprotein enzyme (meaning it contains both RNA and protein) that functions as a reverse transcriptase. Its main role is to add repetitive DNA sequences (TTAGGG in humans) to the ends of chromosomes, which are called telomeres . This counters the natural shortening that occurs during normal DNA replication, a phenomenon known as the "end-replication problem." Telomerase activity is essential in germ cells and stem cells to maintain their proliferative capacity and is also reactivated in approximately 90% of cancer cells, contributing to their limitless cell division.

Explanation of Other Options

  • Repairing damaged DNA strands: This is the function of a different set of proteins and enzymes, such as DNA ligase and various endonucleases, which are part of the DNA repair pathways.

  • Supporting RNA transcription: The primary enzyme for creating an RNA molecule from a DNA template is RNA polymerase.

  • Assisting in DNA duplication: The core process of synthesizing a new DNA strand is carried out by the DNA polymerase enzyme complex.